4-Chloromethcathinone
Pair of enantiomers
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ECHA InfoCard | 100.257.446 |
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Formula | C 10 H 12 Cl N O |
Molar mass | 197.66 g·mol −1 |
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Melting point | 198 °C (388 °F) |
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4-Chloromethcathinone (also known as 4-CMC and Clephedrone ) is a stimulant drug of the cathinone class that has been sold online as a designer drug . [1] [2] [3]
The exact pharmacology of 4-CMC is unknown, though it is probably a dopamine and serotonin releasing agent. Its chemical structure closely resembles para-Chloromethamphetamine and studies involving mice indicate that it is neurotoxic. [4]
Legality
Clephedrone is an Anlage I controlled drug in Germany.
Sweden's public health agency suggested classifying 4-Chloromethcathinone (klefedron) as illegal narcotic on June 1, 2015. [5]
As of October 2015 4-CMC is a controlled substance in China. [6]
4-CMC is considered a Schedule 1 substance in Virginia. [7]
In December 2019, the UNODC announced scheduling recommendations placing 4-CMC into Schedule II. [8]
See also
References
- ↑ "4-Chloromethcathinone" . Cayman Chemical . Retrieved 5 September 2015 .
- ↑ Taschwer M, Weiß JA, Kunert O, Schmid MG (November 2014). "Analysis and characterization of the novel psychoactive drug 4-chloromethcathinone (clephedrone)" . Forensic Science International . 244 : e56-9. doi : 10.1016/j.forsciint.2014.09.007 . PMID 25280452 .
- ↑ Klavž J, Gorenjak M, Marinšek M (August 2016). "Suicide attempt with a mix of synthetic cannabinoids and synthetic cathinones: Case report of non-fatal intoxication with AB-CHMINACA, AB-FUBINACA, alpha-PHP, alpha-PVP and 4-CMC". Forensic Science International . 265 : 121–4. doi : 10.1016/j.forsciint.2016.01.018 . PMID 26890319 .
- ↑ Wojcieszak, Jakub & Kuczyńska, Katarzyna & Zawilska, Jolanta. (2020). Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles. Neurotoxicity Research. 38. 10.1007/s12640-020-00227-8
- ↑ "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 1 June 2015 . Retrieved 5 September 2015 .
- ↑ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015 . Retrieved 1 October 2015 .
- ↑ "18VAC110-20-322. Placement of Chemicals in Schedule I." Commonwealth of Virginia. 2 December 2015 . Retrieved 11 March 2016 .
- ↑ "December 2019 – WHO: World Health Organization recommends 12 NPS for scheduling" .
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