Metanephrine
Chemical compound
Names | |
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IUPAC name
4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
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Identifiers | |
3D model (
JSmol
)
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ChEMBL | |
ChemSpider |
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MeSH | Metanephrine |
PubChem
CID
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UNII | |
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Properties | |
C 10 H 15 NO 3 | |
Molar mass | 197.231 g/mol |
Except where otherwise noted, data are given for materials in their
standard state
(at 25
°C [77
°F], 100
kPa).
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This article is about Specific molecule "metanephrine". For Metanephrines group, see
Metanephrines
.
Metanephrine ( metadrenaline ) is a metabolite of epinephrine ( adrenaline ) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association , 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine ) is the best tool in the diagnosis of pheochromocytoma , an adrenal medullary neoplasm . [1]
References
- ↑ Lenders J, Pacak K, Walther M, Linehan W, Mannelli M, Friberg P, Keiser H, Goldstein D, Eisenhofer G (2002). "Biochemical diagnosis of pheochromocytoma: which test is best?" . JAMA . 287 (11): 1427–34. doi : 10.1001/jama.287.11.1427 . PMID 11903030 . Free full text with registration
catecholamines |
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tryptophan → serotonin |
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serotonin → melatonin |