5-MeO-2-TMT
Chemical compound
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Formula | C 14 H 20 N 2 O |
Molar mass | 232.327 g·mol −1 |
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5-Methoxy-2, N , N -trimethyltryptamine ( 5-MeO-2, N , N -TMT , 5-MeO-TMT ) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic . It was first synthesized by Alexander Shulgin and reported in his book TiHKAL ("Tryptamines i Have Known And Loved"). [1] 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75–150 mg orally, but these are relatively mild compared to those of other similar compounds . This suggests that while the methyl group on the 2-position of the molecule has impaired the binding of metabolic enzymes like monoamine oxidase (MAO), it is also interfering with binding to and/or activation of the serotonin 5-HT 2A receptor , the target responsible for mediating the hallucinogenic effects of such compounds.
See also
- 2, N , N -Trimethyltryptamine (2, N , N -TMT)
- 5-MeO-7-TMT
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