5-Fluoro-MET
Chemical compound
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Other names | 5F-MET |
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Formula | C 13 H 17 F N 2 |
Molar mass | 220.291 g·mol −1 |
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5-Fluoro-MET ( 5F-MET , 5-fluoro- N -methyl- N -ethyltryptamine ) is a psychedelic tryptamine derivative related to drugs such as 5-Fluoro-DMT and N-Methyl-N-ethyltryptamine (MET). It acts as an agonist at the 5-HT 2A receptor with an EC 50 of 20.6 nM and produces a head-twitch response in animal studies. Ring fluorination in this case increases efficacy at 5-HT 2A , with 5F-MET having an efficacy of 87.6% vs 5-HT , vs 36.2% for the partial agonist MET. It is claimed to have antidepressant activity. [1]
See also
References
- ↑ WO 2021/168082 , Kruegel AC, Sporn J, "Specific Tryptamines for use in the Treatment of Mood Disorders.", published 26 August 2021, assigned to Gilgamesh Pharmaceuticals, Inc..
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