JWH-185
Chemical compound
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Formula | C 25 H 27 N O |
Molar mass | 357.497 g·mol −1 |
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JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081 . The binding affinity of JWH-185 for the CB 1 receptor is reported as K i = 17 ± 3 nM. [1]
In the United States, all CB 1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-185 are Schedule I Controlled Substances . [2]
See also
References
- ↑ Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem . 11 (4): 539–549. doi : 10.1016/s0968-0896(02)00451-0 . PMID 12538019 . S2CID 29107765 .
- ↑ 21 U.S.C. § 812 : Schedules of controlled substances
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