Benoxathian
Chemical compound
![]() |
|
Names | |
---|---|
IUPAC name
N
-(2,3-Dihydro-1,4-benzoxathiin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine
|
|
Identifiers | |
3D model (
JSmol
)
|
|
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard
(
EPA
)
|
|
|
|
|
|
Properties | |
C 19 H 23 N O 4 S | |
Molar mass | 361.46 g·mol −1 |
Except where otherwise noted, data are given for materials in their
standard state
(at 25
°C [77
°F], 100
kPa).
|
Benoxathian is an α 1 -adrenergic receptor antagonist . [1] It was studied in animals for its antihypertensive (blood pressure lowering) effects in the 1980s. [2]
References
- ↑ Nagayasu, K; Kitaichi, M; Nishitani, N; Asaoka, N; Shirakawa, H; Nakagawa, T; Kaneko, S (2013). "Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: High potency of milnacipran in the augmentation of serotonin release" . The International Journal of Neuropsychopharmacology . 16 (10): 2295–306. doi : 10.1017/S1461145713000771 . PMID 23920436 .
- ↑ Massi, M.; Venturi, F.; Brasili, L.; Melchiorre, C. (1986). "Hypotensive effect in dogs and rats of intravenous injections of the alpha 1-adrenoreceptor antagonist benoxathian". Pharmacological Research Communications . 18 (9): 813–829. doi : 10.1016/0031-6989(86)90132-3 . PMID 2879293 .
![]() |
This antihypertensive -related article is a stub . You can help Wikipedia by expanding it . |