Ortho Pharmaceutical
Subsidiary of Johnson and Johnson
Industry | pharmaceutical |
---|---|
Founded | 1931 |
Defunct | 1993 ; 30 years ago ( 1993 ) |
Fate | Merged with McNeil Pharmaceuticals in the US and Janssen Pharmaceutica in Canada (Both are now Johnson & Johnson ) |
Successors | McNeil Pharmaceuticals in the US and Janssen Pharmaceutica in Canada later both became Johnson & Johnson |
Area served
|
United States |
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Ortho Pharmaceutical was initially formed in the United States in 1931 as a subsidiary of Johnson & Johnson to market the first prescription spermicidal contraceptive jelly , Ortho-Gynol .
History
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In the 1940s, Ortho introduced the coil-spring diaphragm , and assisted in the development of the Papanicolaou smear stain to screen for cervical cancer .
In 1963, Ortho introduced the second
oral contraceptive
available in the United States (
Ortho-Novum 10
and
Ortho-Novum 2
, produced by
Syntex
).
In 1964, Ortho bought rights to and marketed the
Gynekoil
(Margulies Coil) and
Lippes Loop
inert plastic
IUDs
in the United States until the mid-1970s and 1985, respectively.
In 1968, Ortho introduced
RhoGAM Rho(D) immune globulin
, the first medication developed to prevent
Rh
hemolytic disease of the newborn
.
In 1973, Ortho and Syntex introduced the first progestogen only pills (mini-pills) available in the United States, Mirconor and Nor-QD .
In 1982, Ortho introduced the first
biphasic
oral contraceptive available in the United States,
Ortho-Novum 10/11
.
In 1984, Ortho introduced the first
triphasic
oral contraceptive available in the United States,
Ortho-Novum 7/7/7
.
In 1989, the
FDA
approved
Ortho Cyclen
containing the first new
progestin
(
norgestimate
) approved in over 20 years in the United States.
In 1992, Ortho introduced
Ortho Tri-Cyclen
in the United States, which in 1996 became the first oral contraceptive with an FDA-approved non-contraceptive
indication
(treatment of moderate
acne
).
From 1995 to 2003, Ortho marketed the
ParaGard
copper T-380A IUD in the United States.
In 2001, Ortho introduced the Ortho Evra transdermal contraceptive patch in the United States.
In 1993, Ortho Pharmaceutical merged with McNeil Pharmaceutical in 1993 to form Ortho-McNeil Pharmaceutical .
In Canada , Ortho Products began operations in Montreal in 1941. The company started with one product and three employees and it was one of the first companies in Canada to make oral contraceptives. Moving to Toronto in 1944, the company outgrew a number of rented facilities until its own facilities were constructed in 1955. Continued growth required a number of plant expansions. Ortho Pharmaceutical Canada merged with McNeil Pharmaceutical Canada in 1991, and merged with Janssen Pharmaceutica Canada in 1995 to form Janssen-Ortho.
See also
References
- "Ortho: A her-story of achievement in women's health". Women's Health Care . 5 (5): 16–20. 2006.
- "Rh disease and the discovery of RhoGAM: A story with a happy ending". Women's Health Care . 5 (5): 21–26. 2006.
- "Janssen-Ortho, Inc. Our History and Today" . 2006. Archived from the original on 2007-12-19 . Retrieved 2007-12-08 .