Michael E. Jung
None
Michael E. Jung
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Jung in 2016
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Born |
(
1947-05-14
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May 14, 1947
(age
76)
New Orleans
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Occupation | Professor |
Michael E. Jung is a Professor of Chemistry in the Department of Chemistry and Biochemistry at the University of California at Los Angeles .
Michael Jung was born May 14, 1947, in New Orleans , Louisiana . [1]
Early life and education
Jung received a B.A. from Rice University in Houston , Texas , in 1969 and a Ph.D. from Columbia University in New York City in 1973 where he did research with Gilbert Stork .
Career
![](http://upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Oxetanocin_A.svg/150px-Oxetanocin_A.svg.png)
![](http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Halomon3D.png/150px-Halomon3D.png)
![](http://upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Enzalutamide-01.svg/150px-Enzalutamide-01.svg.png)
Jung then obtained a NATO Postdoctoral Fellowship to work with Albert Eschenmoser at the Eidgenössische Technische Hochschule in Zürich , Switzerland . In 1974, he joined the faculty at UCLA, where he has spent his career. In 1979 Jung was awarded a Sloan research fellowship. [2]
Jung's research is focused on the development of new reactions for organic synthesis , including the Jung "non-aldol aldol" protocol, an alternate method for obtaining aldol products without using the classical aldol reaction . [3] He has also developed chemical syntheses for a variety of natural products with antitumor and antiviral properties including tedanolides , [4] [5] [6] oxetanocin , [7] halomons , [8] and xestobergsterol . [9] Other research interests include the bridged Robinson annulation and the mixed Lewis acid Diels-Alder process. [10]
![](http://upload.wikimedia.org/wikipedia/commons/thumb/1/11/Apalutamide.svg/220px-Apalutamide.svg.png)
Jung's research group developed an antagonist of the androgen receptor enzalutamide , which is a pharmaceutical drug used for the treatment of hormone refractory prostate cancer . [11] [12] An analog of enzalutamide, apalutamide , was also FDA approved.
Awards
- 2022 IUPAC-Richter Prize
- 2016 Glenn T. Seaborg Medal , UCLA [13]
- 2016 Richard C. Tolman Award , Southern California Section of the American Chemical Society [14]
- 2015 American Association for Cancer Research AACR Awards Team Science Award [15]
- 1995 American Chemical Society Arthur C. Cope Scholar Award [16]
References
- ↑ UCLA, Department of Chemistry and Biochemistry
- ↑ "Past Fellows" . sloan.org .
- ↑ Research Interests , Organic Chemistry Faculty, UCLA
- ↑ Jung, Michael E.; Yoo, Dongwon (January 2008). "Synthesis of the C1–C12 fragment of the tedanolides. Selective hydroboration–protonation of allylic alcohol approach". Tetrahedron Letters . 49 (5): 816–819. doi : 10.1016/j.tetlet.2007.11.181 .
- ↑ Jung, Michael E.; Lee, Christopher P. (February 2001). "Synthesis of a Fully Functionalized Protected C1−C11 Fragment for the Synthesis of the Tedanolides". Organic Letters . 3 (3): 333–336. doi : 10.1021/ol000329p . PMID 11428007 .
- ↑ Jung, Michael E; Lee, Christopher P (December 2000). "Use of the non-aldol aldol process in the synthesis of the C1–C11 fragment of the tedanolides: use of lactol ethers in place of tetrahydrofurans". Tetrahedron Letters . 41 (50): 9719–9723. doi : 10.1016/s0040-4039(00)01726-3 .
- ↑ Jung, Michael E.; Nichols, Christopher J. (October 1996). "Highly stereoselective synthesis of trans,trans-4-aryl-2,3-oxetanedimethanols: Preparation of oxetanocin a analogues". Tetrahedron Letters . 37 (43): 7667–7670. doi : 10.1016/0040-4039(96)01720-0 .
- ↑ Jung, Michael E.; Parker, Michael H. (1 October 1997). "Synthesis of Several Naturally Occurring Polyhalogenated Monoterpenes of the Halomon Class1". The Journal of Organic Chemistry . 62 (21): 7094–7095. doi : 10.1021/jo971371+ . ISSN 0022-3263 . PMID 11671809 .
- ↑ Jung, Michael E; Johnson, Ted W (February 2001). "First total synthesis of xestobergsterol A and active structural analogues of the xestobergsterols". Tetrahedron . 57 (8): 1449–1481. doi : 10.1016/s0040-4020(00)01086-3 .
- ↑ Current Research Interest , UCLA
- ↑ "New Prostate Cancer Agent Class: Rational design leads to novel drug candidate, now in clinical trials", Chemical and Engineering News , September 22, 2008, Volume 86, Number 38 pp. 84-87
- ↑ UCLA Chemistry and Biochemistry
- ↑ "UCLA Glenn T. Seaborg Symposium - Previous Recipients" . www.seaborg.ucla.edu .
- ↑ "2015 Michael E. Jung, UCLA" . SCALACS . 24 March 2016.
- ↑ "AACR Team Science Award" . www.aacr.org .
- ↑ "Arthur C. Cope Scholar Awards" . American Chemical Society .
Authority control
: Academics
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