Juanita Merchant
American gastroenterologist and physiology researcher
Juanita L. Merchant
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Juanita L. Merchant is an American gastroenterologist and physiology researcher who has contributed to understanding of gastric response to chronic inflammation. [1] [2] She is currently the chief of the University of Arizona Division of Gastroenterology and Hepatology. [3] [4] Merchant was elected to the National Academy of Medicine in 2008, [5] and appointed an inaugural member of the NIH Council of Councils. [6]
Early life and education
Merchant grew up in Los Angeles . Her mother was an elementary school teacher. [7] She attended Stanford University , where she received her B.S. degree in biology. She went on to Yale University where she received both her M.D. and Ph.D. degrees in 1984. Merchant was the first African-American to earn a dual degree in medicine and cell biology from the Yale School of Medicine . [8] She completed her internal medicine residency and a research fellowship in gastroenterology at the Massachusetts General Hospital in Boston and her clinical fellowship in gastroenterology at UCLA . [9] Merchant is board certified by the American Board of Internal Medicine in both Internal Medicine (1987) and Gastroenterology (1993). [10]
Research and career
After completing her clinical fellowship at UCLA in 1991, Merchant was recruited to the University of Michigan , where she was the H. Marvin Pollard Professor of Gastrointestinal Sciences in Internal Medicine in the Division of Gastroenterology and Molecular and Integrative Physiology. She additionally held a faculty appointment in the University of Michigan Cellular and Molecular Biology Graduate Program. [9] In 1994, Merchant was selected as an Howard Hughes Medical Institute (HHMI) Investigator; this appointment provided support for her research on gastrointestinal-tract cell growth and differentiation until 2002. [11] [12] In 2018, Merchant joined the faculty at the University of Arizona College of Medicine , where she is the chief of the UA Division of Gastroenterology and Hepatology as well as a professor of medicine in the UA Department of Medicine and a member of the Cancer Biology Research Program at the UA Cancer Center. [13] [14]
Merchant's research focuses on molecular mechanisms of gastric cancer biology, in particular the pathways involved in chronic inflammation processes. Since 1993, Merchant has been funded by NIDDK for a project on the " Transcriptional Control of Gastrin ," which focuses on understanding the origin of gastrinomas . [15] In 2002, Merchant and collaborators found that antibiotics did a better job of treating gastritis in mice than blocking acid production with proton pump inhibitors . [16] Merchant holds a patent (granted in 2016) for a biomarker that can help diagnose Irritable Bowel Syndrome (IBS) and Crohn's Disease . [17] In 2018, Merchant was awarded additional NIH funding to study "MDSC Polarization and Helicobacter-Induced Gastric Metaplasia;" this grant will support the study of the role of the Sonic hedgehog (SHH) gene in gastric cancer. [18] Her research has led to authorship or co-authorship on over 100 research publications [19] and she has been the editor or co-editor of multiple books, such as the textbook Physiology of the Gastrointestinal Tract . [20]
Awards and honors
- 1998 Elected to the American Society for Clinical Investigation [21]
- 1998 Robert and Sally Funderburg Award for Gastric Cancer, American Gastroenterological Association [22]
- 2008 Elected to National Academy of Medicine [5]
- 2008-2016 Member of the NIH Council of Councils [6]
- 2008 Outstanding AGA Women in Science Honoree [23]
- 2012 Harold R. Johnson Award for Diversity, University of Michigan [24]
- 2014 AGA Institute Council Section Research Mentor Award in Cellular & Molecular Gastroenterology [25]
- 2014 Sarah Goddard Power Award, University of Michigan [26]
- 2016-2021 Member of the NIDDK Board of Scientific Counselors [27]
- 2017 Distinguished Achievement Award in Basic Science, American Gastroenterological Association [28]
- 2019-2022 Member of National Academy of Medicine Governing Council [29]
References
- ↑ "Helicobacter, Hedgehog Signaling & Gastric Cancer | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
- ↑ Merchant, JL; Du, M; Todisco, A (19 January 1999). "Sp1 phosphorylation by Erk 2 stimulates DNA binding". Biochemical and Biophysical Research Communications . 254 (2): 454–61. doi : 10.1006/bbrc.1998.9964 . PMID 9918860 .
- ↑ "Faculty and Staff - Division of Gastroenterology and Hepatology | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
- ↑ "Message from the Chief | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
- 1 2 "Juanita L. Merchant" . NAM.edu . National Academy of Medicine . Retrieved 12 May 2017 .
- 1 2 "NIH Council of Councils Members Named" . NIH.gov . National Institutes of Health. March 24, 2008 . Retrieved 12 May 2017 .
- ↑ "Juanita L. Merchant, MD, PhD" . University of Michigan Medical School . 2017-02-03 . Retrieved 2020-06-10 .
- ↑ Blair, Jenny. "A long voyage: Juanita Merchant's trip to the top of her field" . Yale School of Medicine . Retrieved 2020-06-10 .
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1
2
"Juanita Merchant, M.D., Ph.D."
Meharry Medical College
. Retrieved
2020-06-10
.
{{ cite web }}
: CS1 maint: url-status ( link ) - ↑ "Juanita Lynne Merchant | ABIM.org" . www.abim.org . Retrieved 2020-06-10 .
- ↑ "Juanita L. Merchant" . HHMI.org . Retrieved 2020-06-10 .
- ↑ "The New Hughes Investigators" . The Scientist Magazine® . Retrieved 2020-06-10 .
- ↑ "Juanita L. Merchant, MD, PhD | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
- ↑ "National Expert on Colon Cancer Begins as Gastroenterology Chief at UA/Banner | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
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↑
"2R01DK045729-24A1, TRANSCRIPTIONAL CONTROL OF GASTRIN"
.
projectreporter.nih.gov
. Retrieved
2020-06-10
.
{{ cite web }}
: CS1 maint: url-status ( link ) - ↑ "Pain in the gut? Don't blame stomach acid" . EurekAlert! . Retrieved 2020-06-10 .
- ↑ "Improving Diagnostics and Treatment for Functional Bowel Disease – Office of Technology Transfer – University of Michigan" . techtransfer.umich.edu . Retrieved 2020-06-10 .
-
↑
"1R01DK118563-01, MDSC POLARIZATION AND HELICOBACTER-INDUCED GASTRIC METAPLASIA"
.
projectreporter.nih.gov
. Retrieved
2020-06-10
.
{{ cite web }}
: CS1 maint: url-status ( link ) - ↑ "Merchant Juanita - Search Results" . PubMed . Retrieved 2020-06-10 .
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↑
Physiology of the gastrointestinal tract
. Said, Hamid M.,, Ghishan, Fayez K. (Sixth
ed.). London. 8 March 2018.
ISBN
978-0-12-812426-0
.
OCLC
1028731517
.
{{ cite book }}
: CS1 maint: others ( link ) - ↑ "The American Society for Clinical Investigation" . Retrieved 2020-06-10 .
- ↑ Goldenring, James R. (2017-05-01). "The AGA/Funderburg Award in Gastric Cancer: Twenty-five Years of Advances in Gastric Cancer Research" . Gastroenterology . 152 (6): 1262–1266. doi : 10.1053/j.gastro.2017.03.010 . ISSN 0016-5085 . PMID 28327368 .
- ↑ "Two U-M doctors recognized as outstanding women in science by AGA | Michigan Medicine" . www.uofmhealth.org . Retrieved 2020-06-10 .
- ↑ "Office of the Provost | Harold R. Johnson Diversity Service Award" . www.provost.umich.edu . Retrieved 2020-06-10 .
- ↑ "AGA Institute Council Section Research Mentor Award" . gastroaws.nclud.com . Retrieved 2020-06-10 .
- ↑ "Sarah Goddard Power Award | Center for the Education of Women | University of Michigan" . www.cew.umich.edu . Retrieved 2020-06-10 .
- ↑ "News Around NIDDK, Summer 2018 | Director's Update | NIDDK" . National Institute of Diabetes and Digestive and Kidney Diseases . Retrieved 2020-06-10 .
- ↑ "Distinguished Achievement Award in Basic Science" . American Gastroenterological Association . Retrieved 2020-06-10 .
- ↑ "UA Gastroenterology Chief Dr. Juanita Merchant Elected to National Academy of Medicine Governing Council | Department of Medicine" . deptmedicine.arizona.edu . Retrieved 2020-06-10 .
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